Acne on back lesions
Virtually universal in the middle to late teenage years, acne on back affects both males and females, although males tend to have more severe disease. Acne is seen in all races, but it is said to be milder in people of Asian descent. Acne on back in adolescents is believed to occur as a result of physiologic hormonal variations and alterations in hair follicle maturation. The clinical features of acne may be induced or exacerbated by drugs (corticosteroids, adrenocorticotropic hormone, testosterone, gonadotropins, contraceptives, trimethadione, iodides, and bromides), occupational contactants (cutting oils, chlorinated hydrocarbons, and coal tars), and occlusive conditions such as heavy clothing and tropical climates. Some families seem to be particularly affected by acne, suggesting a heritable factor..
Acne on back is divided into noninflammatory and inflammatory types, although both may coexist. The former consists of open and closed comedones. Open comedones consist of small follicular papules containing a central black keratin plug. This color is the result of oxidation of melanin pigment (not dirt). Closed comedones are follicular papules without a visible central plug. Because the keratin plug is trapped beneath the epidermal surface, these lesions are potential sources of follicular rupture and inflammation. Inflammatory acne is characterized by erythematous papules, nodules, and pustules. Severe variants (e.g. acne conglobata) result in sinus tract formation and physical scarring, in addition to the emotional scars.
MORPHOLOGY.
Comedones form as an expanding mass of lipid (sebum) and keratin within the midportion of the hair follicle. With gradual expansion, the follicle becomes dilated and the follicular epithelium and sebaceous glands atrophy. Resultant open comedones have large, patulous orifices, whereas those of closed comedones are identifiable only microscopically. Variable lymphohistiocytic infiltrates are present in and around affected follicles, and extensive acute and chronic inflammation accompanies follicular rupture. Dermal abscesses may form in association with rupture, and gradual resolution, often with scarring, ensues.
The pathogenesis of Acne
Endocrine factors have been implicated (especially androgens) because castrated persons never develop the condition. However, these do not appear to be the sole or primary cause. It has been postulated that bacterial lipases of Propionibacterium acnes break down sebaceous oils, liberating highly irritating fatty acids resulting in the earliest inflammatory phases of acne. Inhibition of lipase production is a rationale for administration of antibiotics to patients with inflammatory acne. The synthetic vitamin A derivative 13- cis-retinoic acid (isotretinoin) has brought about remarkable clinical improvement in some cases of severe acne.
Acne on back and the appearance industry
Monday, June 16, 2008
Acne on back lesions
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